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Molfinity

M-110 - CAS 1395048-49-3

M-110 - CAS 1395048-49-3

MF-0015270-01

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Product Details

  • Bioactivity

    M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases, showing a preference for PIM-3 (IC50=47 nM), and inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 also inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.

  • Target

    Pim

  • Related Pathways

    Chromatin/Epigenetic, JAK/STAT signaling

  • CAS Number

    1394996

  • Purity

    0.9955

  • Molecular Formula

    C22H28ClN5O3

  • Molecular Weight

    445.94

  • SMILES

    CC\C(=N/NC(=O)c1ccnc(NCCCN2CCOCC2)c1)c1ccc(Cl)cc1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound