M-APTA - CAS 86072-47-1

M-APTA (5'-S- (3-aminophenyl) -5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP) . It can be converted into adenine, which is a crucial step in shielding normal cells from the toxicity of nucleobase analogs (NBA) . m-APTA holds potential for research in MTAP-deficient cancers.

Phosphorylase

Metabolism

86024

C16H18N6O3S

374.418

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CSC4=CC(N)=CC=C4)[C@H]1O

-20°C

Ice Packs

Small Compound