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M-PEG4-Br - CAS 110429-45-3
M-PEG4-Br - CAS 110429-45-3
SKU:MF-0033268-01
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Product Details
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Bioactivity
M-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC) for Trastuzumab, positioned distally from the monomethyl auristatin E (MMAE) payload to produce an ADC with modified hydrophilicity, antigen binding, and in vitro potency[1].
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Target
PROTAC Linker, ADC Linker
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Related Pathways
Antibody-drug Conjugate/ADC Related, PROTAC
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CAS Number
110381
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Molecular Formula
C9H19BrO4
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Molecular Weight
271.15
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SMILES
COCCOCCOCCOCCBr
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC