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Molfinity

M1002 - CAS 823830-85-9

M1002 - CAS 823830-85-9

SKU:MF-0094888-01

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  • Bioactivity

    M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD) .

  • Target

    HIF/HIF Prolyl-Hydroxylase, HIF

  • Related Pathways

    Chromatin/Epigenetic, Metabolism, Angiogenesis

  • CAS Number

    823736

  • Purity

    0.9998

  • Molecular Formula

    C15H8F6N2O2S

  • Molecular Weight

    394.29

  • SMILES

    FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound