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M1002 - CAS 823830-85-9
M1002 - CAS 823830-85-9
SKU:MF-0094888-01
Regular price
$42.89 USD
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Sale price
$42.89 USD
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Product Details
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Bioactivity
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD) .
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Target
HIF/HIF Prolyl-Hydroxylase, HIF
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Related Pathways
Chromatin/Epigenetic, Metabolism, Angiogenesis
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CAS Number
823736
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Purity
0.9998
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Molecular Formula
C15H8F6N2O2S
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Molecular Weight
394.29
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SMILES
FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound