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M2I-1 - CAS 312271-03-7
M2I-1 - CAS 312271-03-7
SKU:MF-0094594-01
Regular price
$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays.
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Target
Others, Chk
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Related Pathways
Others, Cell Cycle/Checkpoint
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CAS Number
312271-03-7
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Purity
>99.99%
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Molecular Formula
C19H24N4O4S
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Molecular Weight
404.48
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SMILES
CC(C)CN(CC(C)C)c1ccc(C=C2C(=O)NC(=S)NC2=O)cc1[N+]([O-])=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound