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M4K2163 dihydrochloride - CAS 2863635-04-3

M4K2163 dihydrochloride - CAS 2863635-04-3

MF-0120143-01

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Product Details

  • Bioactivity

    M4K2163 dihydrochloride, a potent and selective activin receptor-like kinase-2 (ALK2) inhibitor that is permeable to the blood-brain barrier (BBB), has an IC50 of 19 nM. This compound is useful in diffuse intrinsic pontine glioma (DIPG) research [1] [2].

  • Target

    TGF-beta/Smad, Others

  • Related Pathways

    Stem Cells, Others

  • CAS Number

    2863635-04-3

  • Molecular Formula

    C24H28Cl2FN3O2

  • Molecular Weight

    480.4

  • SMILES

    CC=1C(C2=CC(OC)=C(F)C(OC)=C2)=CN=CC1C3=CC=C(C=C3)N4CCNCC4.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound