M4K2234 - CAS 2421141-51-5

M4K2234 (Compound 26b) is a selective inhibitor of ALK2, displaying IC50 values of 5 nM for ALK2 and 2144 nM for ALK5. As a chemical probe for ALK1 and ALK2 kinases, it is used in mechanistic studies of BMP signaling and in cancer research where dysregulated ALK2 activity is implicated. Its high selectivity profile supports targeted investigations into ALK-mediated pathways.

ALK

Angiogenesis, Tyrosine Kinase/Adaptors

2421085

0.9999

C27H31FN4O2

462.56

O=C(N)C1=C(F)C=C(C=C1OC)C2=CN=CC(C3=CC=C(C=C3)N4CCN(CC4)C(C)C)=C2C

-20°C

Ice Packs

Small Compound