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Molfinity

M62812 - CAS 613263-00-6

M62812 - CAS 613263-00-6

MF-0095014-01

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL) . Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.

  • Target

    TLR

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    613263-00-6

  • Purity

    0.9907

  • Molecular Formula

    C13H13Cl2N3OS

  • Molecular Weight

    330.23

  • SMILES

    Cl.Cl.NC1=NSC2=C1C=CC(OC1=C(N)C=CC=C1)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound