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M8891 - CAS 1464842-09-8
M8891 - CAS 1464842-09-8
SKU:MF-0022855-01
Regular price
$1,383.80 USD
Regular price
Sale price
$1,383.80 USD
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Product Details
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Bioactivity
M8891 is an orally active, reversible, and brain-penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor (IC50: 54 nM; Ki: 4.33 nM) . It inhibits the growth of primary endothelial cells and tumor cells, demonstrating both antiangiogenic and antitumoral activity.
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Target
Others, Aminopeptidase
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Related Pathways
Metabolism, Others
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CAS Number
1464842-09-8
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Molecular Formula
C20H17F2N3O3
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Molecular Weight
385.36
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SMILES
O[C@@]1(CCN(C1=O)c1ccc2[nH]ccc2c1)C(=O)NCc1cc(F)cc(F)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound