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MA242 free base - CAS 1049704-17-7
MA242 free base - CAS 1049704-17-7
SKU:MF-0052484-01
Regular price
$1,927.85 USD
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$1,927.85 USD
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Product Details
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Bioactivity
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. It binds directly to MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated MDM2 transcription.
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Target
MDM-2/p53, Apoptosis, Others
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Related Pathways
Apoptosis, Others
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CAS Number
1049680
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Molecular Formula
C24H20ClN3O3S
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Molecular Weight
465.95
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SMILES
S(=O)(=O)(N1C2=C3C(=C1)CCN=C3C=C(NCC4=CC=C(Cl)C=C4)C2=O)C5=CC=C(C)C=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound