Mabuterol free base - CAS 56341-08-3

Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10 (-7) g/ml and decreased the maximum driving frequency at 3 X 10 (-6) g/ml. Mabuterol was 3 times more potent in relaxing the isolated rat uterus, but 700 times less potent than isoprenaline in relaxing the rabbit jejunum. Mabuterol (p.o.) depressed the intestinal propulsion and was equipotent to isoprenaline and 2.5 times less potent than salbutamol.

Others, Adrenergic Receptor

GPCR/G Protein, Neuroscience, Others

56341-08-3

C13H18ClF3N2O

310.74

FC(F)(F)C1=CC(=CC(Cl)=C1N)C(O)CNC(C)(C)C

-20°C

Ice Packs

Small Compound