Macitentan-d4 - CAS 1258428-05-5

Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor) .Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.

Endothelin Receptor, Apoptosis

GPCR/G Protein, Apoptosis

1258428-05-5

0.9651

C19H20Br2N6O4S

592.3

N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3

-20°C

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