Macitentan (n-butyl analogue) - CAS 556797-16-1

Macitentan n-butyl analogue, a derivative of Macitentan, functions as an orally active dual antagonist targeting both endothelin ETA and ETB receptors. This compound shows promise for treating idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH), leveraging its non-peptide structure for potential therapeutic applications.

Others, Endothelin Receptor

GPCR/G Protein, Others

556780

C20H21Br2N5O4S

587.29

CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1

-20°C

Ice Packs

Small Compound