Molfinity
Macluraxanthone - CAS 5848-14-6
Macluraxanthone - CAS 5848-14-6
SKU:MF-0015484-01
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Product Details
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Bioactivity
Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory and immunomodulatory effects. macluraxanthone promotes the polarization of M1-like pro-inflammatory macrophages by increasing the percentage of macrophages expressing CD86 while decreasing their expression of CD14, CD11b and CD80. Macluraxanthone significantly reduced the production of TNF-α and IL-10 cytokines in the presence of the pro-inflammatory stimulant lipopolysaccharide.
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Target
Antioxidant, TNF
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Related Pathways
Oxidation-Reduction, Apoptosis
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CAS Number
5828
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Molecular Formula
C23H22O6
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Molecular Weight
394.42
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SMILES
O=C1C2=CC=C(O)C(O)=C2OC=3C1=C(O)C=4C=CC(OC4C3C(C=C)(C)C)(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product