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Macluraxanthone - CAS 5848-14-6

Macluraxanthone - CAS 5848-14-6

SKU:MF-0015484-01

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  • Bioactivity

    Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory and immunomodulatory effects. macluraxanthone promotes the polarization of M1-like pro-inflammatory macrophages by increasing the percentage of macrophages expressing CD86 while decreasing their expression of CD14, CD11b and CD80. Macluraxanthone significantly reduced the production of TNF-α and IL-10 cytokines in the presence of the pro-inflammatory stimulant lipopolysaccharide.

  • Target

    Antioxidant, TNF

  • Related Pathways

    Oxidation-Reduction, Apoptosis

  • CAS Number

    5828

  • Molecular Formula

    C23H22O6

  • Molecular Weight

    394.42

  • SMILES

    O=C1C2=CC=C(O)C(O)=C2OC=3C1=C(O)C=4C=CC(OC4C3C(C=C)(C)C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product