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Molfinity
Madindoline A - CAS 184877-64-3
Madindoline A - CAS 184877-64-3
SKU:MF-0126185-01
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Product Details
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Bioactivity
Madindoline A is an IL-6 inhibitor. It suppresses IL-6-dependent MH-60 cells but has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, Madindoline A inhibits IL-6-dependent MH-60 cells with an IC50 of 8 μM. Madindoline A does not exhibit antibacterial activity.
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Target
Interleukin
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Related Pathways
Immunology/Inflammation
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CAS Number
184877-64-3
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Molecular Formula
C22H27NO4
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Molecular Weight
369.454
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SMILES
C(N1[C@@]2([C@](O)(C=3C1=CC=CC3)CCO2)[H])[C@@]4(C)C(=O)C(CCCC)=C(C)C4=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product