MAGL-IN-222 - CAS 877804-65-4

MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor that targets monoacylglycerol lipase (MAGL), with an IC50 of 42.31 μM. It reduces the breakdown of 2-arachidonoylglycerol (2-AG), enhancing intracellular 2-AG levels, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 is applicable in breast cancer research and related diseases.

Lipase

Metabolism

877735

C22H25N3O4S

427.517

N#CC=1C(=O)N(C(=O)C(=CC2=CC=C(C=C2)N(CC)CC)C1C)C3CCS(=O)(=O)C3

-20°C

Ice Packs

Small Compound