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MAK683-CH2CH2COOH - CAS 2639882-68-9
MAK683-CH2CH2COOH - CAS 2639882-68-9
SKU:MF-0031673-01
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$3,279.20 USD
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$3,279.20 USD
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Product Details
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Bioactivity
MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein) and, together with a VHL ligand for the E3 ubiquitin ligase, has been used to design EED-Targeted PROTACs, specifically EED degrader-1 and PROTAC EED degrader-2 [1].
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Target
Histone Methyltransferase, Ligands for Target Protein for PROTAC, Others
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Related Pathways
Chromatin/Epigenetic, Others, PROTAC
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CAS Number
2639805
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Molecular Formula
C23H21FN6O3
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Molecular Weight
448.45
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SMILES
N(CC1=C2C(OCC2)=CC=C1F)C=3N4C(C(=CN3)C5=C(C)N=C(CCC(O)=O)C=C5)=NN=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC