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Mal-C6-α-Amanitin - CAS 1578249-76-9
Mal-C6-α-Amanitin - CAS 1578249-76-9
SKU:MF-0140092-01
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Product Details
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Bioactivity
Mal-C6-α-Amanitin, an ADC (antibody-drug conjugate) linker drug, incorporates the powerful antitumor agent α-Amanitin, an inhibitor of RNA polymerase II, through the Mal-C6 linker, showcasing potent antitumor activity.
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
1578164
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Molecular Formula
C55H78N12O17S
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Molecular Weight
1211.34
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SMILES
[H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CS(=O)c3[nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC