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Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine - CAS 2249935-19-9
Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine - CAS 2249935-19-9
SKU:MF-0154905-01
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Product Details
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Bioactivity
Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine is a linker–payload small molecule of an immune-stimulating antibody conjugate (ISAC), consisting of the STING agonist (ADU-S100) and a cleavable linker. Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine can be used in cancer research.
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Target
Drug-Linker Conjugates for ADC, EGFR, STING
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Related Pathways
Immunology/Inflammation, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Antibody-drug Conjugate/ADC Related
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CAS Number
2249907
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Molecular Formula
C51H65N17O19P2S2.xC6H15N
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Molecular Weight
1447.44
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SMILES
CCN(CC)CC.[H][C@@]12COP(S)(=O)O[C@@]3([H])[C@@H](OC(=O)CCCN(C)C(=O)OCc4ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCN5C(=O)C=CC5=O)C(C)C)cc4)[C@@H](O[C@]3([H])COP(S)(=O)O[C@]([H])([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(N)ncnc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound