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Molfinity

Mambalgin 1 - CAS 1609937-15-6

Mambalgin 1 - CAS 1609937-15-6

SKU:MF-0020303

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  • Bioactivity

    Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively) . Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Increases latency of withdrawal response in mouse tail-flick and paw-flick tests. Analgesic.

  • Target

    Sodium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1609937-15-6

  • Molecular Formula

    C272H429N85O84S10

  • Molecular Weight

    6554.51

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide