Manassantin B - CAS 88497-88-5

Manassantin B is a potent inhibitor of NF-ÎoB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-ÎoB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.

TNF, STAT, JNK, ERK, Antifection, NF-κB, Bcl-2 Family, p38 MAPK

Apoptosis, NF-κB, Microbiology/Virology, MAPK, JAK/STAT signaling, Stem Cells

88404

C41H48O11

716.81

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-20°C

Ice Packs

Natural Product