Manumycin E - CAS 156250-43-0

Manumycin E exhibits activity against Gram-positive bacteria and Escherichia coli, but has limited effect on other Gram-negative bacteria and none on fungi. It inhibits RAS farnesyltransferase and demonstrates modest cytotoxic activity against the human colorectal cancer cell line [HCT-116].

Antibiotic, Antibacterial

Microbiology/Virology

156250-43-0

C30H34N2O7

534.6

C(=C/C=C/C=C/C(NC=1C(=O)CCC1O)=O)\[C@@]2(O)[C@]3([C@](O3)(C(=O)C(NC(/C=C/C=C/C=C/CCC(C)C)=O)=C2)[H])[H]

-20°C

Ice Packs

Natural Product