MAO-B-IN-44 - CAS 1454707-25-5

MAO-B-IN-44 (Compound 4n) is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.01 μM, demonstrating weak inhibition of MAO-A (IC50=14.4 μM) . It reduces the degradation of neurotransmitters like dopamine and holds potential for research into neurodegenerative diseases such as Parkinson's disease, which are associated with MAO-B abnormalities.

Monoamine Oxidase

Neuroscience

1454677

C34H32N4O8

624.64

O=C(OCC)C1=C(NC2=CC=C(OC)C=C2)CC(C3=CC=C(C=C3)N(=O)=O)N(C4=CC=C(OC)C=C4)C1C5=CC=C(C=C5)N(=O)=O

-20°C

Ice Packs

Small Compound