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Molfinity

MAP855 - CAS 1660107-77-6

MAP855 - CAS 1660107-77-6

SKU:MF-0042374-01

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  • Bioactivity

    MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.

  • Target

    ERK, MEK, Others

  • Related Pathways

    Others, MAPK

  • CAS Number

    1660024

  • Molecular Formula

    C28H23ClF2N6O3

  • Molecular Weight

    564.97

  • SMILES

    [H][C@@]1(CCN(C[C@@H]1F)C(=O)CO)n1c(C)nc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2ncccn2)cc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound