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MAP855 - CAS 1660107-77-6
MAP855 - CAS 1660107-77-6
SKU:MF-0042374-01
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$1,041.58 USD
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$1,041.58 USD
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Product Details
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Bioactivity
MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.
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Target
ERK, MEK, Others
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Related Pathways
Others, MAPK
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CAS Number
1660024
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Molecular Formula
C28H23ClF2N6O3
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Molecular Weight
564.97
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SMILES
[H][C@@]1(CCN(C[C@@H]1F)C(=O)CO)n1c(C)nc2cnc3cc(F)c(cc3c12)-c1ccc(Oc2ncccn2)cc1Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound