Masitinib - CAS 790299-79-5

Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

Src, c-Kit, PDGFR, FAK, c-Fms, Apoptosis, FGFR, Bcr-Abl, Hck

Cytoskeletal Signaling, Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors

790215

>99.99%

C28H30N6OS

498.64

N(C1=NC(=CS1)C=2C=CC=NC2)C3=CC(NC(=O)C4=CC=C(CN5CCN(C)CC5)C=C4)=CC=C3C

-20°C

Ice Packs

Small Compound