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Masitinib mesylate - CAS 1048007-93-7

Masitinib mesylate - CAS 1048007-93-7

MF-0012270-01

$39.15 USD
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Product Details

  • Bioactivity

    Masitinib mesylate (AB-1010 mesylate) is a selective, orally bioavailable c-Kit inhibitor with an IC50 of 200 nM for human recombinant c-Kit, and IC50 values of 540/800 nM and 510 nM for PDGFRα/β and LynB, respectively.

  • Target

    PDGFR, c-Kit, FAK, Apoptosis, FGFR, Src

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1048007-93-7

  • Purity

    >99.99%

  • Molecular Formula

    C29H34N6O4S2

  • Molecular Weight

    594.75

  • SMILES

    CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound