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MAT2A-IN-20 - CAS 3018834-98-2

MAT2A-IN-20 - CAS 3018834-98-2

MF-0112842-01

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Product Details

  • Bioactivity

    MAT2A-IN-20 (Compound A49) is an inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC50 of ≤50 nM. It also inhibits human UGT1A1 with an IC50 of 28.45 μM. Additionally, MAT2A-IN-20 exhibits antitumor activity in mouse models.

  • Target

    Methionine Adenosyltransferase (MAT)

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    3018734

  • Molecular Formula

    C26H24F2N6O4

  • Molecular Weight

    522.503

  • SMILES

    O=C1C(=NC=2C=NC(=NC2N1C3=CC=C(OC(F)F)C=C3)OCC)C=4C=CC=5N=C(N(C5C4)C)C(O)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound