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MAT2A-IN-21 - CAS 3062073-94-0
MAT2A-IN-21 - CAS 3062073-94-0
SKU:MF-0113082-01
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Product Details
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Bioactivity
MAT2A-IN-21 (compound 28) is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 of 49 nM. It selectively inhibits cancer cells with MTAP deficiency.
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Target
Methionine Adenosyltransferase (MAT)
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Related Pathways
Chromatin/Epigenetic
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CAS Number
3061979
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Molecular Formula
C26H20F2N4O2
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Molecular Weight
458.459
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SMILES
O=C1C(=NC=2C=CC(=CC2N1C3=CC=C(OC(F)F)C=C3)C4CC4)C=5C=CC=6N=CN(C6C5)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound