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Mavorixafor - CAS 558447-26-0

Mavorixafor - CAS 558447-26-0

SKU:MF-0094804-01

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  • Bioactivity

    Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM) .

  • Target

    CXCR, HIV Protease

  • Related Pathways

    Immunology/Inflammation, Proteases/Proteasome, GPCR/G Protein, Autophagy, Microbiology/Virology

  • CAS Number

    558421

  • Purity

    0.9856

  • Molecular Formula

    C21H27N5

  • Molecular Weight

    349.47

  • SMILES

    N(CC=1NC=2C(N1)=CC=CC2)(CCCCN)[C@@H]3C=4C(CCC3)=CC=CN4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound