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Mavorixafor trihydrochloride - CAS 2309699-17-8

Mavorixafor trihydrochloride - CAS 2309699-17-8

SKU:MF-0004375-01

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  • Bioactivity

    Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM) .

  • Target

    CXCR, HIV Protease

  • Related Pathways

    Autophagy, GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology, Proteases/Proteasome

  • CAS Number

    2309674

  • Molecular Formula

    C21H30Cl3N5

  • Molecular Weight

    458.86

  • SMILES

    Cl.Cl.Cl.NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound