MBM-17S - CAS 2083621-91-2

MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis. It demonstrates antitumor activities without evident toxicity to mice.

MAPK, Aurora Kinase, Apoptosis

MAPK, Cell Cycle/Checkpoint, Chromatin/Epigenetic, Apoptosis

2083528

C36H40N6O10

716.74

O=C(CCC(O)=O)O.O=C(C1=C(OCC2=CC=CC=C2)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)C=C1)N.O=C(CCC(O)=O)O

-20°C

Ice Packs

Small Compound