MBM-55 - CAS 2083622-09-5

MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

Apoptosis, Chk, Akt, GSK-3, DYRK, MAPK, Aurora Kinase, S6 Kinase, CDK, Bcr-Abl

Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Apoptosis, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, MAPK, Stem Cells

2083622-09-5

0.9998

C28H27FN6O2

498.55

CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1

-20°C

Ice Packs

Small Compound