MBM-55S - CAS 2083624-07-9

MBM-55S is an effective inhibitor of Nek2 with an IC50 of 1 nM. MBM-55S indecus cell cycle arrest and apoptosis thereby inhibiting the proliferation of cancer cells. MBM-55S shows antitumor activities.

S6 Kinase, GSK-3, DYRK, Aurora Kinase, MAPK, Akt, Apoptosis, CDK, Bcr-Abl

Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Stem Cells, MAPK, Apoptosis, Cell Cycle/Checkpoint, Angiogenesis

2083624-07-9

0.9989

C36H39FN6O10

734.73

O=C(CCC(O)=O)O.O=C(C1=C(OCC2=CC(F)=CC=C2)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)C=C1)N.O=C(CCC(O)=O)O

-20°C

Ice Packs

Small Compound