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MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin - CAS 2414594-29-7
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin - CAS 2414594-29-7
SKU:MF-0046481-01
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Product Details
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Bioactivity
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a) is a camptothecin payload used in the synthesis of a camptothecin antibody-drug conjugate (ADC) by conjugating it to a monoclonal antibody (mAb) .
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2414558
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Molecular Formula
C44H51FN8O12
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Molecular Weight
902.934
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SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)cc4c(CNC(=O)COCNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCCN4C(=O)C=CC4=O)c3Cn1c2=O |c:58|
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound