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MC-betaglucuronide-MMAE-2 - CAS 1703778-81-7
MC-betaglucuronide-MMAE-2 - CAS 1703778-81-7
SKU:MF-0159090-01
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Product Details
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Bioactivity
MC-betaglucuronide-MMAE-2 is an ADC (antibody-drug conjugate) agent-linker conjugate that exhibits potent antitumor activity; it consists of MMAE (a tubulin polymerization inhibitor) connected through the cleavable linker MC-betaglucuronide.
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
1703778-81-7
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Molecular Formula
C63H93N9O20
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Molecular Weight
1296.46
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SMILES
[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC(NC(CCNC([C@H](CN)N4C(=O)C=CC4=O)=O)=O)=C(O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound