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MC-GGFG-AM- (10NH2-11F-Camptothecin) - CAS 2873460-71-8
MC-GGFG-AM- (10NH2-11F-Camptothecin) - CAS 2873460-71-8
SKU:MF-0159088-01
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Product Details
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Bioactivity
MC-GGFG-AM- (10NH2-11F-Camptothecin) is an antibody-drug conjugate (ADC) that exhibits antitumor activity by targeting TROp-2 with the sacituzumab antibody through a hydrolysable, pH-sensitive linker. It is utilized in cancer research [1].
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Target
Drug-Linker Conjugates for ADC
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
2873460-71-8
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Molecular Formula
C45H45FN8O11
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Molecular Weight
892.88
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SMILES
O=C1N2C(C=3C(C2)=CC=4C(N3)=CC(F)=C(NC(CNC([C@H](CC5=CC=CC=C5)NC(CNC(CNC(CCCCCN6C(=O)C=CC6=O)=O)=O)=O)=O)=O)C4)=CC7=C1COC(=O)[C@]7(CC)O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound