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MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan - CAS 2414393-22-7

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan - CAS 2414393-22-7

SKU:MF-0156383-01

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  • Bioactivity

    MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprised of an ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and the DNA topoisomerase I inhibitor, Exatecan. This conjugate is utilized in cancer research [1].

  • Target

    Topoisomerase, Drug-Linker Conjugates for ADC

  • Related Pathways

    DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

  • CAS Number

    2414364

  • Molecular Formula

    C55H60FN9O13

  • Molecular Weight

    1074.12

  • SMILES

    N(C(=O)C1(OCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O)=O)=O)CCC1)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound