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MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan - CAS 2414393-22-7
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan - CAS 2414393-22-7
SKU:MF-0156383-01
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Product Details
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Bioactivity
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprised of an ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and the DNA topoisomerase I inhibitor, Exatecan. This conjugate is utilized in cancer research [1].
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Target
Topoisomerase, Drug-Linker Conjugates for ADC
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Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
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CAS Number
2414364
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Molecular Formula
C55H60FN9O13
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Molecular Weight
1074.12
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SMILES
N(C(=O)C1(OCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O)=O)=O)CCC1)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound