MC-Gly-Gly-Phe-Gly- (S) -Cyclopropane-Exatecan - CAS 2414254-52-5

MC-Gly-Gly-Phe-Gly- (S) -Cyclopropane-Exatecan is a agent-linker conjugates for ADC , consisting Exatecan . Exatecan is a DNA Topoisomerase I inhibitor (IC 50 =2.2 μM) [1] .

Drug-Linker Conjugates for ADC, Topoisomerase

Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

2414197

C55H60FN9O13

1074.12

CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)[C@@H](OCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)C6CC6)c(c3Cn1c2=O)c45

-20°C

Ice Packs

Small Compound