MC-SN38 - CAS 1473403-87-0

MC-SN38 is a drug-linker conjugate that pairs the potent microtubule-disrupting agent SN38 with a non-cleavable MC linker, designed for use in antibody drug conjugates (ADCs) . SN38, the active metabolite of the Topoisomerase I inhibitor Irinotecan, works by inhibiting DNA synthesis and inducing DNA single-strand breaks.

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

1473316

C32H31N3O8

585.6

CCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)CCCCCN4C(=O)C=CC4=O)c3=O)-c2nc2ccc(O)cc12

-20°C

Ice Packs

Small Compound