MC-Val-Cit-PAB-dimethylDNA31 - CAS 1639352-06-9

MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate employed in antibody-drug conjugates (ADCs) that exhibits robust antitumor efficacy. This conjugate utilizes the ADC linker, MC-Val-Cit-PAB, to connect with the potent antitumor agent dimethylDNA31, which also demonstrates significant bactericidal activity against both persister and stationary-phase [Staphylococcus aureus].

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

1639352-06-9

C78H101N10O19

1482.69

O=C1C=2C=3C=4C(=C5C(=O)C3C(O)=C(C)C2O[C@]1(C)O/C=C\[C@](OC)([C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(/C)\C(=O)N5)[H])OC=6C(N4)=C(O)C=C(C6)N7CCC([N+](CC8=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN9C(=O)C=CC9=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C8)(C)C)CC7

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