Mca-KPLGL-Dap (Dnp) -AR-NH2 TFA - CAS 1392300-20-7

Mca-KPLGL-Dap (Dnp) -AR-NH2 serves as a fluorogenic substrate specifically designed for matrix metalloproteinases (MMPs) . This compound facilitates the quantification of MMP activity by releasing 7-methoxycoumarin-4-acetyl (Mca) upon enzymatic cleavage by MMPs, which exhibits fluorescence with excitation and emission maxima at 328 nm and 420 nm, respectively.

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1392300-20-7

C55H80N16O16.CF3COOH

1335.4

OC(C(F)(F)F)=O.O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CNC2=C(C=C(C=C2)[N+]([O-])=O)[N+]([O-])=O)=O)=O)=O)=O)[C@H](CCCCN)NC(CC(C3=CC=C(OC)C=C3O4)=CC4=O)=O

-20°C

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