MCC950 sodium - CAS 256373-96-3

MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs) . MCC950 sodium has no effect on other inflammatory vesicles such as AIM2, NLRC4 or NLRP1.

NOD-like Receptor (NLR), NOD

Immunology/Inflammation, NF-κB

256274

0.998

C20H23N2O5S·Na

426.46

[Na+].CC(C)(O)c1coc(c1)S(=O)(=O)[N-]C(=O)Nc1c2CCCc2cc2CCCc12

-20°C

Ice Packs

Small Compound