MCH (human, mouse, rat) - CAS 128315-56-0

MCH (human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively) . Increases food intake in vivo.

Melanin-concentrating Hormone Receptor (MCHR), GPCR

Endocrinology/Hormones, GPCR/G Protein

128315-56-0

0.9955

C105H160N30O26S4

2386.84

C([C@H](NC(=O)[C@H]1NC(=O)C2(N(C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@H](CC(O)=O)N)=O)=O)CC(O)=O)=O)CCSC)=O)CC(C)C)=O)CCCNC(=N)N)=O)CSSC1)CCC2)[H])C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCC(N)=O)=O)C=5C=6C(NC5)=CC=CC6

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