MCL0020 - CAS 475498-26-1

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115, and >10,000 nM at MC4, MC3, and MC1 receptors, respectively) . It significantly reverses stress-induced anorexia without affecting food intake in free-feeding rats and exhibits anxiolytic-like activity in vivo.

Melanocortin Receptor

Neuroscience, GPCR/G Protein

475471

0.9918

C34H39N7O4

609.72

C([C@H](C(N[C@H](C(N[C@@H](CC1=CC2=C(C=C1)C=CC=C2)C(N)=O)=O)CCCNC(=N)N)=O)NC(C)=O)C3=CC4=C(C=C3)C=CC=C4

-20°C

Ice Packs

Peptide