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Molfinity

McMMAF - CAS 863971-19-1

McMMAF - CAS 863971-19-1

SKU:MF-0033411-01

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  • Bioactivity

    McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.

  • Target

    Drug-Linker Conjugates for ADC, Apoptosis, Microtubule Associated

  • Related Pathways

    Apoptosis, Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling

  • CAS Number

    863951

  • Purity

    >99.99%

  • Molecular Formula

    C49H76N6O11

  • Molecular Weight

    925.16

  • SMILES

    [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(CCCCCN3C(=O)C=CC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC