Molfinity
McMMAF - CAS 863971-19-1
McMMAF - CAS 863971-19-1
SKU:MF-0033411-01
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Product Details
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Bioactivity
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.
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Target
Drug-Linker Conjugates for ADC, Apoptosis, Microtubule Associated
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Related Pathways
Apoptosis, Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
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CAS Number
863951
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Purity
>99.99%
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Molecular Formula
C49H76N6O11
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Molecular Weight
925.16
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SMILES
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(CCCCCN3C(=O)C=CC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC