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Molfinity

MD-222 - CAS 2136246-72-3

MD-222 - CAS 2136246-72-3

MF-0109307-01

$742.35 USD
$742.35 USD
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Product Details

  • Bioactivity

    MD-222, a pioneering, highly potent PROTAC degrader targeting MDM2, efficiently mediates the rapid degradation of MDM2 protein and activates wild-type p53 within cells, showcasing significant anticancer effects[1][2].

  • Target

    MDM-2/p53, PROTACs, E1/E2/E3 Enzyme

  • Related Pathways

    Apoptosis, PROTAC, Ubiquitination

  • CAS Number

    2136171

  • Molecular Formula

    C48H47Cl2FN6O6

  • Molecular Weight

    893.84

  • SMILES

    Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC