MD-224 - CAS 2136247-12-4

MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) concept, and as a new class of anticancer agent.

Mdm2, E1/E2/E3 Enzyme, PROTACs, MDM-2/p53

Ubiquitination, PROTAC, Apoptosis

2136231

>99.99%

C48H43Cl2FN6O6

889.8

O=C1[C@@]2([C@]3(N[C@@H](C(NC4=CC=C(C(NCCCC#CC5=C6C(C(=O)N(C6)C7C(=O)NC(=O)CC7)=CC=C5)=O)C=C4)=O)[C@@H]2C8=C(F)C(Cl)=CC=C8)CCCCC3)C=9C(N1)=CC(Cl)=CC9

-20°C

Ice Packs

PROTAC