MDM2-IN-26 - CAS 1818393-11-1

MDM2-IN-26 (compound A3) is an inhibitor of MDM2 that facilitates the activation of p53's tumor suppressor functions by inhibiting the MDM2-p53 interaction, with MDM2 being the primary negative regulator of p53. This compound is utilized in cancer research [1].

MDM-2/p53

Apoptosis

1818393-11-1

C32H32Cl2F3N3O4

650.52

O=C1[C@@]2(C3(N[C@@H](C(NC45CCC(C(O)=O)(CC4)CC5)=O)[C@@H]2C6=C(F)C(Cl)=CC=C6)CCC(F)(F)CC3)C=7C(N1)=CC(Cl)=CC7

-20°C

Ice Packs

Small Compound