MDM2-p53-IN-16 - CAS 1917350-09-4

MDM2-p53-IN-16 is a potent inhibitor of the MDM2-p53 complex, with an IC 50 value of 4.3 nM for the dissociation of the human p53/MDM2 complex. It effectively reactivates p53, leading to apoptosis and cell-cycle arrest in Glioblastoma Multiforme (GBM) cells, positioning it as a valuable agent for cancer research.

Others, MDM-2/p53

Others, Apoptosis

1917350-09-4

C32H33N3O5

539.62

C(C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(OC)=O)CC(C)C)=O)=O)(=O)C2=C(NC=3C2=CC=CC3)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound