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MDM2/XIAP-IN-2 - CAS 2761969-85-9
MDM2/XIAP-IN-2 - CAS 2761969-85-9
SKU:MF-0147038-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP), promoting MDM2 degradation and impeding XIAP mRNA translation, thereby inhibiting cancer cell proliferation. It exhibits potent activity against the acute lymphoblastic leukemia cell line EU-1, with an IC50 of 0.3 μM [1].
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Target
Others, MDM-2/p53
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Related Pathways
Others, Apoptosis
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CAS Number
2761875
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Molecular Formula
C29H32N2O4S
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Molecular Weight
504.64
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SMILES
S(NC1=CC(C)=C(C)C=C1)(=O)(=O)C=2C=C3C4C(C(NC3=CC2)C5=CC=C(C(C(C)C)=O)C=C5)CCO4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound